Blar i forfatter "Vanić, Željka"

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    • Chapter 11 - Hydrogels as intrinsic antimicrobials 

      Vanić, Željka; Skalko-Basnet, Natasa (Chapter; Bokkapittel, 2019-10-25)
      Hydrogels are currently applied as the vehicles for drugs or active substances, rather than the active contributors to therapeutic activities. With increasing challenges related to antimicrobial resistance against many antibiotics, natural origin hydrogels have become attractive as more than just vehicles. Although many natural polymers exhibit intrinsic antimicrobial properties, these properties ...

    • Chitosan-coated liposomes for topical vaginal therapy: Assuring localized drug effect 

      Jøraholmen, May Wenche; Vanić, Željka; Tho, Ingunn; Škalko-Basnet, Nataša (Journal article; Tidsskriftartikkel; Peer reviewed, 2014)
      The choice of drug therapy in pregnant patients suffering from vaginal infections is limited by the safety profile of the drug. Assuring the efficient topical therapy to avoid systemic absorption is considered the best therapy option. Chitosan-coated liposomes have been developed and optimized to assure localized therapy of clotrimazole. Chitosan was selected as mucoadhesive polymer both to prolong ...

    • In vitro skin models as a tool in optimization of drug formulation 

      Flaten, Gøril Eide; Palac, Zora; Engesland, André; Filipović-Grčić, Jelena; Vanić, Željka; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-07-30)
      (Trans)dermal drug therapy is gaining increasing importance in the modern drug development. To fully utilize the potential of this route, it is important to optimize the delivery of active ingredient/drug into/through the skin. The optimal carrier/vehicle can enhance the desired outcome of the therapy therefore the optimization of skin formulations is often included in the early stages of the ...

    • (Phospho)lipid-based nanosystems for skin administration 

      Vanić, Željka; Holsæter, Ann Mari; Skalko-Basnet, Natasa (Journal article; Tidsskriftartikkel; Peer reviewed, 2015-10)
      Nanotechnology and nanomedicine provide a platform for advanced therapeutic strategies for dermal and transdermal drug delivery. The focus of this review is on the current state-of-art in lipid-based nanotechnology and nanomedicine for (trans)dermal drug therapy. Drug delivery nanosystems based on the (phospho)lipid constituents are characterized and compared, with the emphasis on their ability ...